Early Detection Research Network

TRADD

Aliases:
This biomarker is also known as:
  • TNFR1-associated death domain protein,
  • Hs.89862,
  • TNFR1-associated DEATH domain protein,
  • TNFRSF1A-associated via death domain,
  • TRADD,
  • tumor necrosis factor receptor-1-associated protein,
  • tumor necrosis factor receptor type 1-associated DEATH domain protein,
  • tumor necrosis factor receptor type 1 associated death domain protein,

Description…

From NCBI Gene: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: TRADD

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

No other associated resources found.

Version 5.0.2