Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / TNFAIP1

TNFAIP1

Basics

Aliases:
This biomarker is also known as:
  • BTB/POZ domain-containing protein TNFAIP1,
  • BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation,
  • Tumor necrosis factor, alpha-induced protein 1, endothelial,
  • Protein B12,
  • B12,
  • protein 2,
  • OTTHUMP00000163324,
  • EDP1,
  • B61,
  • hBACURD2,
  • MGC2317,
  • BACURD2,
  • tumor necrosis factor, alpha-induced protein 1,
  • Q13829,

View in BioMuta

Description…

The expression of this gene can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Mouse studies suggest the expression of this gene is developmentally regulated in a tissue-specific manner. Thought to be involved in regulation of cytoskeleton structure.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Under Review

Overview

No additional ovarian data available.

Performance Comment

TNFAIP1 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. TNFAIP1 was not in the group of 13 selected for further validation.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement