Early Detection Research Network

TEK

Aliases:
This biomarker is also known as:
  • tyrosine-protein kinase receptor TIE-2,
  • EC 2.7.10.1,
  • Tyrosine-protein kinase receptor TIE-2,
  • p140 TEK,
  • TEK,
  • TEK tyrosine kinase, endothelial,
  • endothelial tyrosine kinase,
  • tyrosine-protein kinase receptor TEK,
  • CD202B,
  • soluble TIE2 variant 2,
  • TIE2,
  • Tunica interna endothelial cell kinase,
  • tunica interna endothelial cell kinase,
  • VMCM,
  • TIE-2,
  • CD202b antigen,
  • soluble TIE2 variant 1,
  • Tyrosine kinase with Ig and EGF homology domains-2,
  • tyrosine kinase with Ig and EGF homology domains-2,
  • Endothelial tyrosine kinase,
  • venous malformations, multiple cutaneous and mucosal,
  • VMCM1,
  • Tyrosine-protein kinase receptor TEK,
  • hTIE2,
  • angiopoietin-1 receptor,

Description…

From NCBI Gene: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: TEK

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2