Early Detection Research Network

SPINK1

Aliases:
This biomarker is also known as:
  • PSTI,
  • Serine Protease Inhibitor, Kazal Type 1,
  • TATI,
  • TCP,
  • Serine Protease Inhibitor, Kazal-Type 1,
  • Tumor-Associated Trypsin Inhibitor,
  • SPINK1,
  • PCTT,
  • Serine Peptidase Inhibitor, Kazal Type 1,
  • Pancreatic Secretory Trypsin Inhibitor,
  • Spink3,

Description…

SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. Its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Mutations in SPINK1 are associated with hereditary pancreatitis and tropical calcific pancreatitis.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: SPINK1

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2