Early Detection Research Network

RBBP4

Aliases:
This biomarker is also known as:
  • Retinoblastoma-binding protein 4,
  • histone-binding protein RBBP4,
  • nucleosome-remodeling factor subunit RBAP48,
  • RBBP4,
  • CAF-1 subunit C,
  • MSI1 protein homolog,
  • Chromatin assembly factor 1 subunit C,
  • chromatin assembly factor 1 subunit C,
  • retinoblastoma-binding protein p48,
  • RBAP48,
  • Chromatin assembly factor I p48 subunit,
  • chromatin assembly factor/CAF-1 p48 subunit,
  • Nucleosome-remodeling factor subunit RBAP48,
  • retinoblastoma binding protein 4,
  • retinoblastoma-binding protein 4,
  • RbAp48,
  • chromatin assembly factor I p48 subunit,
  • CAF-I p48,
  • RBBP-4,
  • Retinoblastoma-binding protein p48,
  • CAF-I 48 kDa subunit,
  • NURF55,

Description…

From NCBI Gene: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: RBBP4

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2