Early Detection Research Network

PROM1

Aliases:
This biomarker is also known as:
  • antigen AC133,
  • macular dystrophy, retinal 2,
  • CD133 antigen,
  • RP41,
  • Antigen AC133,
  • PROML1,
  • hProminin,
  • AC133,
  • prominin-1,
  • MCDR2,
  • PROM1,
  • prominin 1,
  • Prominin-like protein 1,
  • prominin (mouse)-like 1,
  • Stargardt disease 4 (autosomal dominant),
  • STGD4,
  • prominin-like protein 1,
  • CD133,
  • hematopoietic stem cell antigen,
  • CORD12,

Description…

From NCBI Gene: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: PROM1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2