Early Detection Research Network

PCA3

Aliases:
This biomarker is also known as:
  • DD3,
  • PCA3,
  • prostate cancer antigen 3 (non-protein coding),
  • non-protein coding RNA 19,
  • prostate cancer associated transcript 3 (non-protein coding),
  • NCRNA00019,
  • PCAT3,
  • prostate cancer antigen 3,

Description…

The prostate cancer antigen 3 (PCA3) gene is a highly specific biomarker upregulated in prostate cancer. Because there is no extensive open reading frame, the gene is thought to express a noncoding RNA. The FDA has approved an assay for prostate cancer that uses the ratio of PCA3 RNA to PSA RNA in urine. The assay is used to help physicians determine the need for repeat prostate biopsies in men 50 years of age or older who have had a previous negative biopsy. When used in conjunction with other clinical information, the use of this test can reduce the need for unnecessary prostate biopsies.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: PCA3

The following organs have data associated with this biomarker…

Attributes

Phase: Three
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2