Early Detection Research Network

PARK7

Aliases:
This biomarker is also known as:
  • Parkinson disease (autosomal recessive, early onset) 7,
  • DJ1,
  • Parkinson disease protein 7,
  • Oncogene DJ-1,
  • Protein DJ-1,
  • DJ-1,
  • PARK7,

Description…

DJ-1, also known as PARK-7, belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. DJ-1 is highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart and is detected at slightly lower levels in placenta and brain.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Accepted
Type: Protein
HGNC Name: PARK7

The following organs have data associated with this biomarker…

Attributes

Phase: Three
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.
Version 5.0.2