Early Detection Research Network

OGT

Aliases:
This biomarker is also known as:
  • O-GlcNAc transferase subunit p110,
  • MRX106,
  • O-GlcNAc transferase p110 subunit,
  • FLJ23071,
  • O-linked N-acetylglucosamine (GlcNAc) transferase,
  • O-linked N-acetylglucosamine transferase 110 kDa subunit,
  • OGT,
  • HRNT1,
  • UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase,
  • EC 2.4.1.255,
  • O-GLCNAC,
  • uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase,
  • MGC22921,
  • UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit,
  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase),

Description…

From NCBI Gene: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: OGT

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2