Early Detection Research Network

MCCC2

Aliases:
This biomarker is also known as:
  • EC 6.4.1.4,
  • methylcrotonoyl-Coenzyme A carboxylase 2 (beta),
  • 3-methylcrotonyl-CoA carboxylase 2,
  • biotin carboxylase,
  • 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit,
  • methylcrotonoyl-CoA carboxylase 2 (beta),
  • methylcrotonoyl-CoA carboxylase beta chain, mitochondrial,
  • MCCC2,
  • MCCB,
  • MCCase subunit beta,
  • 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta,
  • non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase,

Description…

From NCBI Gene: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: MCCC2

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2