Early Detection Research Network

LZTS1

Aliases:
This biomarker is also known as:
  • Fez1,
  • Q9Y250,
  • F37/Esophageal cancer-related gene-coding leucine-zipper motif,
  • LZTS1,
  • F37,
  • F37/esophageal cancer-related gene-coding leucine-zipper motif,
  • FEZ1,
  • leucine zipper, putative tumor suppressor 1,
  • leucine zipper putative tumor suppressor 1,

Description…

LZTS1 is a tumor suppressor protein that is widely expressed in normal tissues. It is involved in regulating cell growth and is also thought to interact with the active CDC2-cyclin B1 complex and contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer, and this gene is located on 8p22.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: LZTS1

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2