Early Detection Research Network

IL6

Aliases:
This biomarker is also known as:
  • BSF2,
  • CTL differentiation factor,
  • Hybridoma growth factor,
  • B-cell stimulatory factor 2,
  • BSF-2,
  • Interferon beta-2,
  • CDF,
  • interleukin 6 (interferon, beta 2),
  • HGF,
  • B cell stimulatory factor-2,
  • IL-6,
  • HSF,
  • B-cell differentiation factor,
  • Interleukin 6,
  • IL6,
  • IFN-beta-2,
  • IFNB2,

Description…

Interleukin 6 (IL6) is a cytokine that is involved in inflammation and the maturation of B cells as well as induction of the acute phase response. In addition to inducing myeloma and plasmacytoma growth and nerve cell differentiation, it also plays an important role in the differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. The IL6 protein is produced mainly at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The IL6 gene is involved in many inflammation-associated disease states, including diabetes mellitus, where it acts on insulin resistance, and systemic juvenile rheumatoid arthritis. IL6 is discharged into the bloodstream after muscle contraction.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: IL6

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2