Early Detection Research Network

HSPB1

Aliases:
This biomarker is also known as:
  • Hsp25,
  • Stress-responsive protein 27,
  • heat shock 27kD protein 1,
  • HSP27,
  • heat shock 27 kDa protein,
  • Hs.76067,
  • HSPB1,
  • 28 kDa heat shock protein,
  • HMN2B,
  • CMT2F,
  • Estrogen-regulated 24 kDa protein,
  • HS.76067,
  • SRP27,
  • Heat shock 27 kDa protein,
  • HSP 27,
  • HSP28,
  • stress-responsive protein 27,
  • heat shock 27kDa protein 1,
  • heat shock protein beta-1,
  • HspB1,
  • estrogen-regulated 24 kDa protein,

Description…

From NCBI Gene: This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: HSPB1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2