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GSTZ1

Basics

Aliases:
This biomarker is also known as:
  • maleylacetoacetate isomerase,
  • EC 5.2.1.2,
  • glutathione transferase zeta 1,
  • glutathione s-transferase Zeta 1,
  • glutathione S-alkyltransferase,
  • Glutathione S-transferase zeta 1,
  • GSTZ1-1,
  • EC 2.5.1.18,
  • glutathione S-aryltransferase,
  • glutathione S-aralkyltransferase,
  • S-(hydroxyalkyl)glutathione lyase,
  • MAI,
  • maleylacetone isomerase,
  • MAAI,

View in BioMuta

Description…

The GSTZ1 gene product, glutathione transferase zeta 1, is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is also involved in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Attributes

QA State: Under Review
Type: Gene
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement