Early Detection Research Network

GADD45B

Aliases:
This biomarker is also known as:
  • negative growth regulatory protein MyD118,
  • growth arrest and DNA damage-inducible protein GADD45 beta,
  • GADD45B,
  • MYD118,
  • DKFZP566B133,
  • Myeloid differentiation primary response protein MyD118,
  • Negative growth regulatory protein MyD118,
  • myeloid differentiation primary response protein MyD118,
  • growth arrest and DNA-damage-inducible, beta,
  • GADD45BETA,

Description…

From NCBI Gene: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: GADD45B

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2