Early Detection Research Network

GADD45A

Aliases:
This biomarker is also known as:
  • DNA-damage-inducible transcript 1,
  • growth arrest and DNA-damage-inducible, alpha,
  • DNA damage-inducible transcript 1 protein,
  • growth arrest and DNA-damage-inducible 45 alpha,
  • GADD45A,
  • GADD45,
  • DDIT-1,
  • growth arrest and DNA damage-inducible protein GADD45 alpha,
  • DNA damage-inducible transcript-1,
  • DDIT1,

Description…

From NCBI Gene: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: GADD45A

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2