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ERG

Basics

Aliases:
This biomarker is also known as:
  • V-Ets Erythroblastosis Virus E26 Oncogene Like,
  • Transcriptional Regulator ERG (Transforming Protein ERG),
  • Transforming Protein ERG,
  • V-Ets Avian Erythroblastosis Virus E26 Oncogene Related,
  • Erg,
  • P55,
  • V-Ets Erythroblastosis Virus E26 Oncogene Homolog (Avian),
  • Ets-Related,
  • Transcriptional Regulator ERG,
  • V-Ets Erythroblastosis Virus E26 Oncogene Like (Avian),
  • TMPRSS2/ERG Fusion,

View in BioMuta

Description…

The ERG gene codes for the ERG protein, a transcription factor that is a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. Members of this family are involved in embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. ERG is mainly expressed in the nucleus. ERG is also involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Different isoforms arising from multiple alternatively spliced transcripts have been identified.

Attributes

QA State: Under Review
Type: Gene
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement