Early Detection Research Network

EGFR

Aliases:
This biomarker is also known as:
  • HER1,
  • cell proliferation-inducing protein 61,
  • Proto-oncogene c-ErbB-1,
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog),
  • Receptor tyrosine-protein kinase erbB-1,
  • mENA,
  • ERBB,
  • EGFR,
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,
  • cell growth inhibiting protein 40,
  • c-erbB-1,
  • ERBB1,
  • PIG61,
  • Epidermal growth factor receptor,

Description…

From NCBI Gene: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: EGFR

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Attributes

Phase: Two
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Attributes

Phase: Three
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2