Early Detection Research Network

DBT

Aliases:
This biomarker is also known as:
  • EC 2.3.1.168,
  • Branched Chain Acyltransferase, E2 Component,
  • Dihydrolipoamide Branched Chain Transacylase,
  • BCKADE2,
  • E2,
  • Dihydrolipoyl Transacylase,
  • Dihydrolipoyllysine-Residue (2-Methylpropanoyl)Transferase,
  • E2 Component Of Branched Chain Alpha-Keto Acid Dehydrogenase Complex,
  • E2B,
  • Branched-Chain Alpha-Keto Acid Dehydrogenase Complex Component E2,
  • Lipoamide Acyltransferase Component Of Mitochondrial Branched-Chain Alpha-Keto Acid Dehydrogenase Complex,
  • Dihydrolipoamide Branched Chain Transacylase E2,
  • Lipoamide Acyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex, Mitochondrial,
  • Dihydrolipoamide Branched Chain Transacylase (E2 Component Of Branched Chain Keto Acid Dehydrogenase Complex; Maple Syrup Urine Disease),
  • DBT,
  • BCKAD E2 Subunit,
  • BCKAD-E2,
  • Mitochondrial Branched Chain Alpha-Keto Acid Dehydrogenase Transacylase Subunit (E2b),
  • BCATE2,
  • Dihydrolipoamide Acetyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex,

Description…

From NCBI Gene: The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: DBT

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2