Early Detection Research Network

BCAM

Aliases:
This biomarker is also known as:
  • B-CAM cell surface glycoprotein,
  • basal cell adhesion molecule (Lu and Au blood groups),
  • Basal cell adhesion molecule,
  • Auberger B antigen,
  • Lutheran blood group (Auberger b antigen included),
  • F8/G253 antigen,
  • BCAM,
  • AU,
  • CD239,
  • LU,
  • basal cell adhesion molecule (Lutheran blood group),
  • Lutheran antigen,
  • MSK19,
  • CD_antigen=CD239,
  • Lutheran blood group glycoprotein,

Description…

From NCBI Gene: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: BCAM

The following organs have data associated with this biomarker…

Attributes

Phase: Three
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

No other associated resources found.

Version 5.0.2