Early Detection Research Network

ALDH1A2

Aliases:
This biomarker is also known as:
  • RALDH 2,
  • Aldehyde dehydrogenase family 1 member A2,
  • ALDH1A2,
  • RALDH2,
  • Retinaldehyde-specific dehydrogenase type 2,
  • RalDH2,
  • retinaldehyde-specific dehydrogenase type 2,
  • retinal dehydrogenase 2,
  • aldehyde dehydrogenase 1 family, member A2,
  • RALDH(II),
  • EC 1.2.1.36,
  • RALDH2-T,

Description…

From NCBI Gene: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: ALDH1A2

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2