Early Detection Research Network

ADH5

Aliases:
This biomarker is also known as:
  • alcohol dehydrogenase class chi chain,
  • GSNOR,
  • ADH-3,
  • ADH5,
  • Glutathione-dependent formaldehyde dehydrogenase,
  • Alcohol dehydrogenase class chi chain,
  • alcohol dehydrogenase 5 (class III), chi polypeptide,
  • glutathione-dependent formaldehyde dehydrogenase,
  • alcohol dehydrogenase class-III,
  • alcohol dehydrogenase class-3,
  • formaldehyde dehydrogenase,
  • GSH-FDH,
  • FDH,
  • S-(hydroxymethyl)glutathione dehydrogenase,
  • Alcohol dehydrogenase class-III,
  • Alcohol dehydrogenase 5,
  • ADHX,
  • FALDH,
  • alcohol dehydrogenase (class III), chi polypeptide,
  • EC 1.1.1.1,EC 1.1.1.-,EC 1.1.1.284,

Description…

From NCBI Gene: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: ADH5

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2