Aliases:This biomarker is also known as:
- WW, C2 and coiled-coil domain containing 1,
- WW domain-containing protein 1,
- HBeAg-binding protein 3,
- protein WWC1,
- Kidney and brain protein,
- kidney and brain protein,
- WW and C2 domain containing 1,
- protein KIBRA,
WWC1, or KIBRA, is a cytoplasmic phosphoprotein. Expression has been detected in the brain, heart, colon and kidney, as well as mammary epithelial cells and breast cancer cell lines. WWC1 interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that may be associated with memory performance. Three transcript variants encoding different isoforms have been found for the WWC1 gene.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional ovarian data available.
WWC1 (KIBRA) was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. WWC1 (KIBRA) was not in the group of 13 selected for further validation.
|UniProt Accession #:||Q8IX03|
|Mutated Sites Count:||207|
|Associated Pubmed ID Count||24|
|Affected Protein Function Sites Count:||5|