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WWC1

Basics

Aliases:
This biomarker is also known as:
  • HBEBP3,
  • protein KIBRA,
  • protein WWC1,
  • WW and C2 domain containing 1,
  • Kidney and brain protein,
  • HBeAg-binding protein 3,
  • KIAA0869,
  • WW domain-containing protein 1,
  • KIBRA,
  • HBEBP36,
  • Q8IX03,
  • WW, C2 and coiled-coil domain containing 1,
  • kidney and brain protein,

View in BioMuta

Description…

WWC1, or KIBRA, is a cytoplasmic phosphoprotein. Expression has been detected in the brain, heart, colon and kidney, as well as mammary epithelial cells and breast cancer cell lines. WWC1 interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that may be associated with memory performance. Three transcript variants encoding different isoforms have been found for the WWC1 gene.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: WWC1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: One
QA State: Under Review

Overview

No additional ovarian data available.

Performance Comment

WWC1 (KIBRA) was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. WWC1 (KIBRA) was not in the group of 13 selected for further validation.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement