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You are here: Home / Biomarkers / VTA1



This biomarker is also known as:
  • Dopamine-responsive gene 1 protein,
  • chromosome 6 open reading frame 55,
  • SKD1-binding protein 1,
  • C6ORF55,
  • Vps20-associated 1 homolog (S. cerevisiae),
  • My012,
  • SBP1,
  • dopamine-responsive gene 1 protein,
  • LIP5,
  • C6orf55,
  • HSPC228,
  • homolog of mouse SKD1-binding protein 1,
  • LYST-interacting protein 5,
  • DRG-1,
  • Q9NP79,
  • vacuolar protein sorting-associated protein VTA1 homolog,
  • DRG1,


VTA1 (C6ORF55) is involved in activities of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes. VTA1 is thought to be a cofactor of VPS4A/B. VTA1 is involved in HIV-1 budding. It has been shown by similarity to be involved in the sorting and down-regulation of EGFR.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional ovarian data available.

Performance Comment

VTA1 (C6ORF55) was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. VTA1 (C6ORF55) was not in the group of 13 selected for further validation.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


Mutation Statistics

Gene Name: VTA1
UniProt Accession #: Q9NP79
Mutated Sites Count: 43
Associated Pubmed ID Count 5
CancerDO Count 17
Affected Protein Function Sites Count: 2

View in BioMuta