Aliases:This biomarker is also known as:
- protein 2,
- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation,
- Protein B12,
- BTB/POZ domain-containing protein TNFAIP1,
- tumor necrosis factor, alpha-induced protein 1,
- Tumor necrosis factor, alpha-induced protein 1, endothelial,
The expression of this gene can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Mouse studies suggest the expression of this gene is developmentally regulated in a tissue-specific manner. Thought to be involved in regulation of cytoskeleton structure.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional ovarian data available.
TNFAIP1 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. TNFAIP1 was not in the group of 13 selected for further validation.
|UniProt Accession #:||Q13829|
|Mutated Sites Count:||42|
|Associated Pubmed ID Count||7|
|Affected Protein Function Sites Count:||4|