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You are here: Home / Biomarkers / STOM

STOM

Basics

Aliases:
This biomarker is also known as:
  • stomatin,
  • erythrocyte band 7 integral membrane protein,
  • Protein 7.2b,
  • EPB72,
  • EPB7,
  • erythrocyte surface protein band 7.2,
  • Stomatin,
  • erythrocyte membrane protein band 7.2 (stomatin),
  • BND7,
  • protein 7.2b,

Description…

STOM, or stomatin, is an integral membrane protein located in the cell membrane of red blood cells and other cell types, where it is thought to regulate ion channels and transporters. Multiple transcript variants are produced by alternative splicing.

Attributes

QA State: Curated
Type: Gene
Short Name:
HGNC Name: STOM

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

STOM was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Prostate

Attributes

Phase: One
QA State: Under Review

Overview

Performance Comment

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

External Resources for STOM

This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.

Gene

Protein

Other

No other associated resources found.

Biomuta

Mutation Statistics

Gene Name: STOM
UniProt Accession #: P27105
Mutated Sites Count: 29
Associated Pubmed ID Count 4
CancerDO Count 15
Affected Protein Function Sites Count: 2

View in BioMuta