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SRP54

Basics

Aliases:
This biomarker is also known as:
  • signal recognition particle 54kD,
  • signal recognition particle 54 kDa protein,
  • signal recognition particle 54kDa,

Description…

SRP54, or signal recognition particle 54kDa, contains a 7S RNA molecule of 300 nucleotides and six protein subunits. SRP54 binds to the signal sequence of presecretory proteins as they emerge from the ribosomes and transfers them to a translocating chain-associating membrane protein.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: SRP54

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

SRP54 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: SRP54
UniProt Accession #: P61011
Mutated Sites Count: 100
Associated Pubmed ID Count 12
CancerDO Count 20
Affected Protein Function Sites Count: 4

View in BioMuta