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SLC25A16

Basics

Aliases:
This biomarker is also known as:
  • graves disease carrier protein,
  • graves disease autoantigen,
  • Graves disease autoantigen,
  • mitochondrial solute carrier protein homolog,
  • Mitochondrial solute carrier protein homolog,
  • solute carrier family 25 member 16,
  • GDA,
  • Solute carrier family 25 member 16,
  • hML7,
  • ML7,
  • solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16,
  • GDC,
  • D10S105E,
  • HGT.1,

Description…

SLC25A16 is a member of the mitochondrial carrier family and contains three tandemly repeated mitochondrial carrier protein domains. The SLC26A16 protein is found in the inner membrane of the mitochondria where it is necessary for the accumulation of coenzyme A in the mitochondrial matrix. SLC25A16 also facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. The SLC25A16 gene is thought to be involved in Graves' disease.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: SLC25A16

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

ADH5 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

Resources

Biomuta

Mutation Statistics

Gene Name: SLC25A16
UniProt Accession #: P16260
Mutated Sites Count: 26
Associated Pubmed ID Count 4
CancerDO Count 13
Affected Protein Function Sites Count: 2

View in BioMuta