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RRAGD

Basics

Aliases:
This biomarker is also known as:
  • DKFZP761H171,
  • RAGD,
  • Ras-related GTP binding D,
  • Rag D,
  • RagD,
  • Rag D protein,
  • ras-related GTP-binding protein D,
  • bA11D8.2.1,

Description…

From NCBI Gene: RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]

Attributes

QA State: Curated
Type: Gene
Short Name:
HGNC Name: RRAGD

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Prostate

Attributes

Phase: One
QA State: Curated

Overview

No additional prostate data available.

Performance Comment

Significance Analysis of Microarray (SAM) was used to develop a 7-gene classifier. The overall prediction accuracy and sensitivity is 71% and 76%, respectively. The inclusion of the Gleason sum to the seven-gene classifier raised the prediction accuracy and sensitivity to 83% and 76% respectively This prognostic signature is closely associated with biochemical recurrence in patients after radical prostatectomy. The seven genes are: RRAGD, PQBP1, HIST1H2BC, ALDH1A2, TRIM22, RBPMS, HSPB8.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: RRAGD
UniProt Accession #: Q9NQL2
Mutated Sites Count: 46
Associated Pubmed ID Count 8
CancerDO Count 18
Affected Protein Function Sites Count: 4

View in BioMuta