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RHOA

Basics

Aliases:
This biomarker is also known as:
  • RhoA,
  • ARHA,
  • RHOH12,
  • rho cDNA clone 12,
  • ARH12,
  • Aplysia ras-related homolog 12,
  • small GTP binding protein RhoA,
  • oncogene RHO H12,
  • RHO12,
  • ras homolog gene family, member A,
  • h12,
  • Rho cDNA clone 12,
  • transforming protein RhoA,
  • Rho12,
  • ras homolog family member A,

View in BioMuta

Description…

RHOA is a member of the small GTPase superfamily. RHO family GTPases are involved in many basic cellular processes that influence cell proliferation, differentiation, motility, adhesion, survival, or secretion. RHOA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: RHOA

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

RHOA has been shown to be involved in hypoxia-inducible factor-mediated RHOA expression and signaling in breast cancer cells.

Performance Comment

RHOA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement