Aliases:This biomarker is also known as:
- quiescin Q6,
- quiescin Q6 sulfhydryl oxidase 1,
- Sulfhydryl oxidase 1,
QSCN6 contains domains of thioredoxin and ERV1, members of two long-standing gene families. QSCN6 catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. It may contribute to disulfide bond formation in a variety of secreted proteins. The QSCN6 gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. In fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.
|QA State:||Under Review|
There are no datasets associated with this biomarker.