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MYCBP

Basics

Aliases:
This biomarker is also known as:
  • AMY-1,
  • c-myc binding protein,
  • AMY1,
  • associate of myc-1,
  • Associate of Myc 1,
  • C-Myc-binding protein,

Description…

MYCBP, or MYC binding protein, or C-MYC binding protein, binds to the N-terminus of the oncogenic protein MYC, also known as C-MYC, enhancing the ability of MYC to activate E box-dependent transcription. MYCBP is normally found in the cytoplasm, but it moves to the nucleus during the S phase of the cell cycle and associates with MYC.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: MYCBP

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

MYCBP was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: MYCBP
UniProt Accession #: Q99417
Mutated Sites Count: 10
Associated Pubmed ID Count 3
CancerDO Count 10
Affected Protein Function Sites Count: 3

View in BioMuta