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This biomarker is also known as:
  • miRNA21,
  • microRNA 21,
  • mir-21,
  • MIRN21,
  • hsa-mir-21,
  • miR-21,


From NCBI Gene: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. miRNAs bind to complementary sequences in the 3' UTR of multiple target mRNAs, usually silencing the targeted mRNA. miRNAs may trigger the cleavage of their target molecules or act as translational repressors. miRNAs are thought to target approximatley 60% of all genes and are able to repress hundreds of targets each.


QA State: Curated
Type: Genomic
Short Name:
HGNC Name: MIR21


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Curated


MIR21 has been associated with many types of cancer, including lung, breast, pancreatic, and prostate.

Performance Comment

MIR21 is one of four members of a panel investigated as potential plasma biomarkers for non-small-cell lung cancer (NSCLC). The four members of the panel are MIR486-5p, MIR21, MIR126, MIR210.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


No associated Biomuta entries found.