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LCP2

Basics

Aliases:
This biomarker is also known as:
  • SH2 domain-containing leukocyte protein of 76 kDa,
  • SLP76,
  • SH2 domain-containing leukocyte protein of 76kD,
  • SLP-76,
  • SLP-76 tyrosine phosphoprotein,
  • lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD),
  • lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa),
  • 76 kDa tyrosine phosphoprotein,
  • lymphocyte cytosolic protein 2,

View in BioMuta

Description…

LCP2, previously known as SLP76, functions as an adaptor or scaffolding protein. LCP2 has three modular domains. The amino-terminal end has an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. LCP2 also contains a central proline-rich domain and a COOH-terminal SH2 domain.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: LCP2

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

LCP2 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement