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KRAS

Basics

Aliases:
This biomarker is also known as:
  • c-K-ras2 protein,
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,
  • KI-RAS,
  • RASK2,
  • NS,
  • K-RAS4B,
  • NS3,
  • transforming protein p21,
  • oncogene KRAS2,
  • C-K-RAS,
  • KRAS2,
  • PR310 c-K-ras oncogene,
  • Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,
  • KRAS1,
  • K-RAS2B,
  • cellular c-Ki-ras2 proto-oncogene,
  • K-RAS4A,
  • K-ras p21 protein,
  • c-Kirsten-ras protein,
  • K-RAS2A,

View in BioMuta

Description…

The KRAS gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: KRAS

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement