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ITGBL1

Basics

Aliases:
This biomarker is also known as:
  • Ten integrin EGF-like repeat domain-containing protein,
  • Osteoblast-specific cysteine-rich protein,
  • TIED,
  • ten integrin EGF-like repeat domains protein,
  • osteoblast-specific cysteine-rich protein,
  • OSCP,
  • ten integrin EGF-like repeat domain-containing protein,
  • integrin, beta-like 1 (with EGF-like repeat domains),
  • integrin beta-like protein 1,

Description…

ITGBL1, or integrin, beta-like 1 (with EGF-like repeat domains), is a member of the EGF-like protein family. It is a beta integrin-related protein containing integrin-like cysteine-rich repeats. Multiple transcript variants result from alternative splicing.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: ITGBL1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

ITGBL1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

External Resources for ITGBL1

This gene encodes a beta integrin-related protein that is a member of the EGF-like protein family. The encoded protein contains integrin-like cysteine-rich repeats. Alternative splicing results in multiple transcript variants.

Gene

Protein

Other

Biomuta

Mutation Statistics

Gene Name: ITGBL1
UniProt Accession #: O95965
Mutated Sites Count: 373
Associated Pubmed ID Count 18
CancerDO Count 20
Affected Protein Function Sites Count: 2

View in BioMuta