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IL10

Basics

Aliases:
This biomarker is also known as:
  • T-cell growth inhibitory factor,
  • Interleukin-10,
  • IL10A,
  • IL-10,
  • CSIF,
  • interleukin 10,
  • TGIF,
  • cytokine synthesis inhibitory factor,

View in BioMuta

Description…

Interleukin 10, a secreted protein belonging to the IL-10 family, is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. It down-regulates the expression of cytokines IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells, MHC class II Ags, and costimulatory molecules on macrophages.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: IL10

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Curated

Overview

IL10 alone was not a strong predictor of ovarian cancer.

Performance Comment

Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement