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HSD17B10

Basics

Aliases:
This biomarker is also known as:
  • MRPP2,
  • Short-chain type dehydrogenase/reductase XH98G2,
  • Mitochondrial ribonuclease P protein 2,
  • amyloid-beta peptide binding alcohol dehydrogenase,
  • ABAD,
  • HADH2,
  • AB-binding alcohol dehydrogenase,
  • XH98G2,
  • mitochondrial RNase P subunit 2,
  • MRX17,
  • DUPXp11.22,
  • EC 1.1.1.35,EC 1.1.1.178,
  • SDR5C1,
  • 17b-HSD10,
  • SCHAD,
  • short chain type dehydrogenase/reductase XH98G2,
  • HCD2,
  • MHBD,
  • CAMR,
  • Type II HADH,
  • 3-hydroxyacyl-CoA dehydrogenase type II,
  • hydroxysteroid (17-beta) dehydrogenase 10,
  • ERAB,
  • 17-beta-hydroxysteroid dehydrogenase 10,
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
  • mental retardation, X-linked, syndromic 10,
  • MRXS10,
  • 3-hydroxyacyl-CoA dehydrogenase type-2,
  • short chain dehydrogenase/reductase family 5C, member 1,
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
  • Mitochondrial RNase P protein 2,
  • mitochondrial ribonuclease P protein 2,
  • 17-beta-HSD 10,
  • MRX31,
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,

View in BioMuta

Description…

HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: HSD17B10

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement