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HMGB1

Basics

Aliases:
This biomarker is also known as:
  • High mobility group protein B1,
  • high mobility group box 1,
  • SBP-1,
  • high-mobility group box 1,
  • DKFZp686A04236,
  • Sulfoglucuronyl carbohydrate binding protein,
  • high-mobility group (nonhistone chromosomal) protein 1,
  • HMG3,
  • HMG1,
  • high mobility group protein 1,
  • Amphoterin,

Description…

Nuclear protein HMGB1 is a DNA-binding protein that associates with chromatin and has the ability to bend DNA. It binds preferentially single-stranded DNA. HMGB1 is involved in V(D)J recombination by acting as a cofactor of the RAG complex. It acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS).

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: HMGB1

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.