Personal tools

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit

Updates regarding government operating status and resumption of normal operations can be found at

You are here: Home / Biomarkers / HIST1H2BF



This biomarker is also known as:
  • H2BFK,
  • histone cluster 1, H2bf,
  • H2BFH,
  • H2BFG,
  • H2B/l,
  • Histone H2B.l,
  • H2BFL,
  • H2B/k,
  • Histone H2B.1 A,
  • Histone H2B.h,
  • H2B/h,
  • Histone H2B.g,
  • H2B histone family, member G,
  • H2B/a,
  • histone 1, H2bf,
  • Histone H2B.k,
  • H2B/g,
  • Histone H2B.a,
  • histone H2B.1 A,
  • histone H2B type 1-C/E/F/G/I,
  • histone H2B.g,
  • H2BFA,


histone cluster 1, H2bf


QA State: Curated
Type: Gene
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: One
QA State: Curated


Performance Comment

Significance Analysis of Microarray (SAM) was used to develop a 7-gene classifier. The overall prediction accuracy and sensitivity is 71% and 76%, respectively. The inclusion of the Gleason sum to the seven-gene classifier raised the prediction accuracy and sensitivity to 83% and 76% respectively This prognostic signature is closely associated with biochemical recurrence in patients after radical prostatectomy. The seven genes are: RRAGD, PQBP1, HIST1H2BC (HIST1H2BE, HIST1H2BF, HIST1H2BI), ALDH1A2, TRIM22, RBPMS, HSPB8.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


Mutation Statistics

Gene Name: HIST1H2BF
UniProt Accession #: P62807
Mutated Sites Count: 29
Associated Pubmed ID Count 6
CancerDO Count 20
Affected Protein Function Sites Count: 3

View in BioMuta