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You are here: Home / Biomarkers / HIST1H2BF

HIST1H2BF

Basics

Aliases:
This biomarker is also known as:
  • H2BFK,
  • histone cluster 1, H2bf,
  • H2BFH,
  • H2BFG,
  • H2B/l,
  • Histone H2B.l,
  • H2BFL,
  • H2B/k,
  • Histone H2B.1 A,
  • Histone H2B.h,
  • H2B/h,
  • Histone H2B.g,
  • H2B histone family, member G,
  • H2B/a,
  • histone 1, H2bf,
  • Histone H2B.k,
  • H2B/g,
  • Histone H2B.a,
  • histone H2B.1 A,
  • histone H2B type 1-C/E/F/G/I,
  • histone H2B.g,
  • H2BFA,

Description…

histone cluster 1, H2bf

Attributes

QA State: Curated
Type: Gene
Short Name:
HGNC Name: HIST1H2BF

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Prostate

Attributes

Phase: One
QA State: Curated

Overview

Performance Comment

Significance Analysis of Microarray (SAM) was used to develop a 7-gene classifier. The overall prediction accuracy and sensitivity is 71% and 76%, respectively. The inclusion of the Gleason sum to the seven-gene classifier raised the prediction accuracy and sensitivity to 83% and 76% respectively This prognostic signature is closely associated with biochemical recurrence in patients after radical prostatectomy. The seven genes are: RRAGD, PQBP1, HIST1H2BC (HIST1H2BE, HIST1H2BF, HIST1H2BI), ALDH1A2, TRIM22, RBPMS, HSPB8.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: HIST1H2BF
UniProt Accession #: P62807
Mutated Sites Count: 29
Associated Pubmed ID Count 6
CancerDO Count 20
Affected Protein Function Sites Count: 3

View in BioMuta