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HEXIM1

Basics

Aliases:
This biomarker is also known as:
  • Menage a quatre protein 1,
  • CLP1,
  • hexamthylene bis-acetamide inducible 1,
  • Cardiac lineage protein 1,
  • EDG1,
  • estrogen down-regulated gene 1 protein,
  • HMBA-inducible,
  • menage a quatre 1,
  • menage a quatre protein 1,
  • Estrogen down-regulated gene 1 protein,
  • protein HEXIM1,
  • hexamethylene bis-acetamide inducible 1,
  • MAQ1,
  • CLP-1,
  • hexamethylene bisacetamide-inducible protein,
  • cardiac lineage protein 1,
  • hexamethylene bis-acetamide-inducible protein 1,
  • hexamethylene-bis-acetamide-inducible transcript 1,
  • HIS1,
  • Hexamethylene bis-acetamide-inducible protein 1,

Description…

HEXIM1 is an intronless transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: HEXIM1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

HEXIM1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: HEXIM1
UniProt Accession #: O94992
Mutated Sites Count: 35
Associated Pubmed ID Count 8
CancerDO Count 15
Affected Protein Function Sites Count: 3

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