Aliases:This biomarker is also known as:
- T-cell death-associated gene 8 protein,
- G-protein coupled receptor 65,
- G protein-coupled receptor 65,
- psychosine receptor,
GPR65, a member of the G-protein coupled receptor 1 family, is a receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. GPR65 may have a role in activation-induced cell death or differentiation of T-cells. It is expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional ovarian data available.
GPR65 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. GPR65 was not in the group of 13 selected for further validation.
- HGNC entry for GPR65 from Genenames
- KEGG entry for GPR65 from Genome.jp
- Entrez entry for GPR65 all NCBI Databasese
- Human GEO Profiles for GPR65 from NCBI GEO Profiles
- Human Geo Datasets containing term GPR65 from NCBI GEO Datasets
- GWAS Study Datasets containing gene GPR65 from GWAS
- Human Single Nucleotide Polymorphisms info for GPR65
- Human Gene(s) with 'GPR65' as Gene Name/Alias
- Human Gene RefSeq for GPR65 from NCBI
- GeneCards entry for human GPR65
- UniProtKB/Swiss-Prot entry for GPR65 from Uniprot
- Human Protein RefSeq for GPR65 from NCBI
- FDA web page describing approval of GPR65
|UniProt Accession #:||Q8IYL9|
|Mutated Sites Count:||76|
|Associated Pubmed ID Count||9|
|Affected Protein Function Sites Count:||5|