Aliases:This biomarker is also known as:
- T-cell death-associated gene 8 protein,
- psychosine receptor,
- G-protein coupled receptor 65,
- G protein-coupled receptor 65,
GPR65, a member of the G-protein coupled receptor 1 family, is a receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. GPR65 may have a role in activation-induced cell death or differentiation of T-cells. It is expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional ovarian data available.
GPR65 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. GPR65 was not in the group of 13 selected for further validation.
External Resources for GPR65
|UniProt Accession #:||Q8IYL9|
|Mutated Sites Count:||76|
|Associated Pubmed ID Count||9|
|Affected Protein Function Sites Count:||5|