Aliases:This biomarker is also known as:
- Growth hormone,
- Pituitary growth hormone,
- growth hormone 1,
- Growth hormone 1,
- pituitary growth hormone,
Growth hormone, a secreted protein which exists as a monomer, dimer, trimer, tetramer and pentamer and is disulfide-linked or non-covalently associated in homopolymeric and heteropolymeric combinations, plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH belongs to the somatotropin/prolactin family.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
GH1 alone was not a strong predictor of ovarian cancer.
Of the ovarian cancer biomarkers tested in prediagnostic specimens, from the PLCO, CA125 remains the single best biomarker for ovarian cancer and has its strongest signal within six months of diagnosis. GH1 alone was not a strong predictor.
No associated publications found.
- HGNC entry for GH1 from Genenames
- KEGG entry for GH1 from Genome.jp
- Entrez entry for GH1 all NCBI Databasese
- Human GEO Profiles for GH1 from NCBI GEO Profiles
- Human Geo Datasets containing term GH1 from NCBI GEO Datasets
- GWAS Study Datasets containing gene GH1 from GWAS
- Human Single Nucleotide Polymorphisms info for GH1
- Human Gene(s) with 'GH1' as Gene Name/Alias
- Human Gene RefSeq for GH1 from NCBI
- GeneCards entry for human GH1
- UniProtKB/Swiss-Prot entry for GH1 from Uniprot
- Human Protein RefSeq for GH1 from NCBI
- FDA web page describing approval of GH1
|UniProt Accession #:||P01241|
|Mutated Sites Count:||98|
|Associated Pubmed ID Count||4|
|Affected Protein Function Sites Count:||4|