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GDF15

Basics

Aliases:
This biomarker is also known as:
  • NSAID-activated gene 1 protein,
  • Placental bone morphogenetic protein,
  • Prostate differentiation factor,
  • PLAB,
  • NAG-1,
  • prostate differentiation factor,
  • PTGFB,
  • MIC1,
  • MIC-1,
  • Macrophage inhibitory cytokine 1,
  • PDF,
  • Placental TGF-beta,
  • GDF-15,
  • NSAID-regulated gene 1 protein,
  • growth differentiation factor 15,
  • NRG-1,

View in BioMuta

Description…

GDF15, also known as macrophage inhibitory cytokine 1, or MIC1, is a bone morphogenetic protein (BMP) belonging to the transforming growth factor-beta (TGF-beta) superfamily. The bone morphogenetic proteins regulate tissue differentiation and maintenance. GDF15 is a secreted protein that is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. Bone morphogenetic protein precursor molecules are cleaved at a dibasic site to release C-terminal domains with 7 conserved cysteines in the mature protein.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: GDF15

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement