Aliases:This biomarker is also known as:
- Follitropin beta chain,
- Follitropin subunit beta,
- follicle-stimulating hormone beta subunit,
- follitropin, beta chain,
- follicle stimulating hormone, beta polypeptide,
Follicle stimulating hormone, a heterodimer glycoprotein of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin, stimulates development of follicle and spermatogenesis in the reproductive organs. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. FSHB belongs to the glycoprotein hormones subunit beta family. There are two transcript variants from alternative splicing that each encode the same protein.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
It is uncertain if FSH levels are related to ovarian cancer risk. Conclusions from different studies show conflicting results.
Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.
- HGNC entry for FSHB from Genenames
- KEGG entry for FSHB from Genome.jp
- Entrez entry for FSHB all NCBI Databasese
- Human GEO Profiles for FSHB from NCBI GEO Profiles
- Human Geo Datasets containing term FSHB from NCBI GEO Datasets
- GWAS Study Datasets containing gene FSHB from GWAS
- Human Single Nucleotide Polymorphisms info for FSHB
- Human Gene(s) with 'FSHB' as Gene Name/Alias
- Human Gene RefSeq for FSHB from NCBI
- UniProtKB/Swiss-Prot entry for FSHB from Uniprot
- Human Protein RefSeq for FSHB from NCBI
- FDA web page describing approval of FSHB
No other associated resources found.
|UniProt Accession #:||P01225|
|Mutated Sites Count:||39|
|Associated Pubmed ID Count||7|
|Affected Protein Function Sites Count:||5|