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This biomarker is also known as:
  • follicle-stimulating hormone beta subunit,
  • FSHB,
  • FSH-B,
  • Follitropin subunit beta,
  • Follitropin beta chain,
  • follicle stimulating hormone, beta polypeptide,
  • follitropin, beta chain,
  • FSH-beta,

View in BioMuta


Follicle stimulating hormone, a heterodimer glycoprotein of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin, stimulates development of follicle and spermatogenesis in the reproductive organs. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. FSHB belongs to the glycoprotein hormones subunit beta family. There are two transcript variants from alternative splicing that each encode the same protein.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Three
QA State: Curated


It is uncertain if FSH levels are related to ovarian cancer risk. Conclusions from different studies show conflicting results.

Performance Comment

Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take on a date and location to be determined.