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FOLH1B

Basics

Aliases:
This biomarker is also known as:
  • EC 3.4.-.-,
  • PSMA-LIKE,
  • cell growth-inhibiting gene 26 protein,
  • PSMAL,
  • Putative folate hydrolase 1B,
  • folate hydrolase 1B,
  • FOLHP,
  • PSM,
  • NAALADase,
  • folate hydrolase pseudogene,
  • putative folate hydrolase 1B,
  • folate hydrolase 2,
  • GCP3,
  • Q9HBA9,
  • FOLH2,
  • GCPIII,
  • N-acetylated-alpha-linked-acidic dipeptidase,
  • prostate-specific membrane antigen-like protein,
  • Prostate-specific membrane antigen-like protein,
  • glutamate carboxypeptidase III,
  • Cell growth-inhibiting gene 26 protein,
  • putative N-acetylated-alpha-linked acidic dipeptidase,

Description…

FOLH1B, or PSMAL, is a cytoplasmic protein. It has been found in the kidney and liver, and has not been detected in the prostate. GO annotations related to this gene include metallopeptidase activity and dipeptidase activity.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: FOLH1B

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: One
QA State: Under Review

Overview

No additional ovarian data available.

Performance Comment

FOLH1B (PSMAL) was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. FOLH1B (PSMAL) was not in the group of 13 selected for further validation.

Prostate

Attributes

Phase: One
QA State: Under Review

Overview

Performance Comment

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: FOLH1B
UniProt Accession #: Q9HBA9
Mutated Sites Count: 114
Associated Pubmed ID Count 17
CancerDO Count 21
Affected Protein Function Sites Count: 4

View in BioMuta