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ERCC4

Basics

Aliases:
This biomarker is also known as:
  • DNA repair endonuclease XPF,
  • xeroderma pigmentosum, complementation group F,
  • EC 3.1.-.-,
  • excision-repair, complementing defective, in Chinese hamster,
  • Xeroderma pigmentosum group F-complementing protein,
  • excision repair cross-complementing rodent repair deficiency, complementation group 4,
  • XPF,
  • DNA repair protein complementing XP-F cells,
  • DNA excision repair protein ERCC-4,
  • xeroderma pigmentosum group F-complementing protein,
  • ERCC11,
  • RAD1,

Description…

ERCC4 is a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. It forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. Mutations in the ERCC4 gene can cause xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Attributes

QA State: Under Review
Type: Gene
Short Name:
HGNC Name: ERCC4

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.