Aliases:This biomarker is also known as:
- EFR3 homolog A (S. cerevisiae),
- protein EFR3 homolog A,
- Protein EFR3-like,
EFR3A (KIAA0143) is a membrane protein. Little is known about its function, although studies on the mouse homolog have suggested a role in hearing. It has been shown in mice that it is differentially expressed in the auditory brainstem neurons of mice with hearing deficit, compared to mice with normal hearing ability.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional ovarian data available.
EFR3A (KIAA0143) was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. EFR3A (KIAA0143) was not in the group of 13 selected for further validation.
|UniProt Accession #:||Q14156|
|Mutated Sites Count:||115|
|Associated Pubmed ID Count||11|
|Affected Protein Function Sites Count:||4|