Aliases:This biomarker is also known as:
- EPH-related receptor tyrosine kinase ligand 7,
- eph-related receptor tyrosine kinase ligand 7,
EFNA5 is a cell surface-bound member of the ephrin gene family. Ephrins are proteins that function as ligands for the ephrin receptors (Eph receptors). Eph receptors are a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional breast data available.
EFNA5 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.
- HGNC entry for EFNA5 from Genenames
- KEGG entry for EFNA5 from Genome.jp
- Entrez entry for EFNA5 all NCBI Databasese
- Human GEO Profiles for EFNA5 from NCBI GEO Profiles
- Human Geo Datasets containing term EFNA5 from NCBI GEO Datasets
- GWAS Study Datasets containing gene EFNA5 from GWAS
- Human Single Nucleotide Polymorphisms info for EFNA5
- Human Gene(s) with 'EFNA5' as Gene Name/Alias
- Human Gene RefSeq for EFNA5 from NCBI
- GeneCards entry for human EFNA5
- UniProtKB/Swiss-Prot entry for EFNA5 from Uniprot
- Human Protein RefSeq for EFNA5 from NCBI
- FDA web page describing approval of EFNA5
|UniProt Accession #:||P52803|
|Mutated Sites Count:||41|
|Associated Pubmed ID Count||4|
|Affected Protein Function Sites Count:||4|