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You are here: Home / Biomarkers / DNAJC7



This biomarker is also known as:
  • DANJC7,
  • DJC7,
  • dnaJ homolog subfamily C member 7,
  • Tetratricopeptide repeat protein 2,
  • DJ11,
  • tetratricopeptide repeat domain 2,
  • TPR repeat protein 2,
  • DnaJ (Hsp40) homolog, subfamily C, member 7,
  • TTC2,
  • TPR2,
  • tetratricopeptide repeat protein 2,


DNAJC7 is a member of the DNAJ heat shock protein 40 family. This family is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. DNAJC7 functions as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. There are pseudogenes of this gene on chromosomes 1 and 6. Multiple transcript variants of DNAJC7 exist from alternate splicing.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

DNAJC7 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


Mutation Statistics

Gene Name: DNAJC7
UniProt Accession #: Q99615
Mutated Sites Count: 78
Associated Pubmed ID Count 6
CancerDO Count 15
Affected Protein Function Sites Count: 2

View in BioMuta